{"id":1327,"date":"2024-07-07T01:43:50","date_gmt":"2024-07-06T23:43:50","guid":{"rendered":"https:\/\/laboratoriosluar.com\/products\/infectology\/fosfomicina\/"},"modified":"2024-07-09T06:58:24","modified_gmt":"2024-07-09T04:58:24","slug":"fosfomicina","status":"publish","type":"page","link":"https:\/\/laboratoriosluar.com\/en\/products\/infectology\/fosfomicina\/","title":{"rendered":"Fosfomicina"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1327\" class=\"elementor elementor-1327 elementor-30\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6b97b4c e-flex e-con-boxed e-con e-parent\" data-id=\"6b97b4c\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d6f4029 e-con-full e-flex e-con e-child\" data-id=\"d6f4029\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-500d29d e-con-full glass-box e-flex e-con e-child\" data-id=\"500d29d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1e60c73 elementor-widget elementor-widget-heading\" data-id=\"1e60c73\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><span class=\"elementor-heading-title elementor-size-default\">Infectology<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b06498 elementor-widget elementor-widget-heading\" data-id=\"8b06498\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Fosfomicina LUAR<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f2e6e8c elementor-widget elementor-widget-heading\" data-id=\"f2e6e8c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">1g injection<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f050e6 elementor-widget elementor-widget-text-editor\" data-id=\"4f050e6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Fosfomicina LUAR is active on methicillin-resistant staphylococci, BLEE- or carbapenemase-producing enterobacteria (such as KPC) and 50% of pseudomonas aeruginosa.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e141f6b elementor-widget elementor-widget-button\" data-id=\"e141f6b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#fosfomicina\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn more<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7d2c3fa e-con-full e-flex e-con e-child\" data-id=\"7d2c3fa\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-18f9da5 e-flex e-con-boxed e-con e-parent\" data-id=\"18f9da5\" data-element_type=\"container\" id=\"fosfomicina\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-889c0e1 e-con-full e-flex e-con e-child\" data-id=\"889c0e1\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6276ffe elementor-widget elementor-widget-image\" data-id=\"6276ffe\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"332\" height=\"127\" src=\"https:\/\/laboratoriosluar.com\/wp-content\/uploads\/2024\/07\/fosfomicina-logo.png\" class=\"attachment-large size-large wp-image-981\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a7367e elementor-widget elementor-widget-heading\" data-id=\"1a7367e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">About Fosfomicina LUAR<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d1d086 elementor-widget elementor-widget-text-editor\" data-id=\"4d1d086\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>It contains <strong>Fosfomycin sodium<\/strong> as active ingredient, and due to the appearance of <strong>strains resistant<\/strong> to conventional antibiotic therapies, it is used in association with other antibiotics, used intravenously.<\/p>\n<p>Fosfomicina LUAR is active on methicillin-resistant staphylococci, BLEE- or carbapenemase-producing enterobacteria (such as KPC) and 50% of pseudomonas aeruginosa. It should always be used in association with another antimicrobial to avoid the emergence of resistant strains.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a259a1e e-con-full e-flex e-con e-child\" data-id=\"a259a1e\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-777f613 elementor-widget elementor-widget-image\" data-id=\"777f613\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"616\" height=\"544\" src=\"https:\/\/laboratoriosluar.com\/wp-content\/uploads\/2024\/07\/fosfomicina-side-img-1.webp\" class=\"attachment-full size-full wp-image-983\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ef30484 e-flex e-con-boxed e-con e-parent\" data-id=\"ef30484\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;shape_divider_top&quot;:&quot;waves&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-shape elementor-shape-top\" data-negative=\"false\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 1000 100\" preserveAspectRatio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M421.9,6.5c22.6-2.5,51.5,0.4,75.5,5.3c23.6,4.9,70.9,23.5,100.5,35.7c75.8,32.2,133.7,44.5,192.6,49.7\n\tc23.6,2.1,48.7,3.5,103.4-2.5c54.7-6,106.2-25.6,106.2-25.6V0H0v30.3c0,0,72,32.6,158.4,30.5c39.2-0.7,92.8-6.7,134-22.4\n\tc21.2-8.1,52.2-18.2,79.7-24.2C399.3,7.9,411.6,7.5,421.9,6.5z\"\/>\n<\/svg>\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7ae7fec e-con-full e-flex e-con e-child\" data-id=\"7ae7fec\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-427d27a e-con-full e-flex e-con e-child\" data-id=\"427d27a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0fc45de elementor-widget elementor-widget-text-editor\" data-id=\"0fc45de\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Consequently, it is compatible with any <strong>antimicrobial<\/strong>, presenting synergic or additive activity independently of their mechanisms of action. <strong>Fosfomycin<\/strong> is active in meningeal, bone, skin and soft tissue, non-prostatic urinary and pulmonary infections.<\/p>\n<p>Administered <strong>intravenously<\/strong>, it has no teratogenic effects, so it can be used in pregnant women. By this route of administration there are no side effects.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-226eb02 e-con-full e-flex e-con e-child\" data-id=\"226eb02\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d60a6b6 e-flex e-con-boxed e-con e-parent\" data-id=\"d60a6b6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-33b6c1f e-con-full e-flex e-con e-child\" data-id=\"33b6c1f\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f1e1c8f elementor-widget elementor-widget-heading\" data-id=\"f1e1c8f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Frequently Asked Questions<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b7deabf elementor-widget__width-initial custom-tabs elementor-widget elementor-widget-accordion\" data-id=\"b7deabf\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-accordion{text-align:start}.elementor-accordion .elementor-accordion-item{border:1px solid #d5d8dc}.elementor-accordion .elementor-accordion-item+.elementor-accordion-item{border-top:none}.elementor-accordion .elementor-tab-title{margin:0;padding:15px 20px;font-weight:700;line-height:1;cursor:pointer;outline:none}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{display:inline-block;width:1.5em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon svg{width:1em;height:1em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-right{float:right;text-align:right}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-left{float:left;text-align:left}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-closed{display:block}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-opened,.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-closed{display:none}.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-opened{display:block}.elementor-accordion .elementor-tab-content{display:none;padding:15px 20px;border-top:1px solid #d5d8dc}@media (max-width:767px){.elementor-accordion .elementor-tab-title{padding:12px 15px}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{width:1.2em}.elementor-accordion .elementor-tab-content{padding:7px 15px}}.e-con-inner>.elementor-widget-accordion,.e-con>.elementor-widget-accordion{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1921\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1921\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-chevron-down\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-chevron-up\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Presentation<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1921\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1921\"><p><strong>Fosfomicina LUAR Intravenous Injectable 1 g<\/strong> is presented in boxes containing 10 and 100 vials.<\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1922\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-1922\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-chevron-down\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-chevron-up\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Efficiency<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1922\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-1922\"><p>In cases <strong>of severe hospital infections<\/strong>, the use of <strong>Fosfomycin<\/strong> in association with other antibiotics is essential to avoid the selection of resistant mutants (chromosomal acquired resistance) as much as possible. Associations with <strong>penicillins<\/strong>, <strong>cephalosporins<\/strong>, <strong>aminoglycosides<\/strong>, <strong>colistin<\/strong>, <strong>vancomycin<\/strong>, are always synergistic and never antagonistic.<\/p>\n<p><strong>Fosfomycin sodium<\/strong> is used in <strong>complicated or severe infections<\/strong> caused by germs sensitive to the drug (Enterococcus faecalis, Streptococcus pneumoniae, methicillin-resistant Staphylococcus, Citrobacter spp , Escherichia coli, Haemophilus influenzae, Klebsiella spp, Neisseria meningitidis, Pasteurella spp, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Pseudomonas spp).<\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1923\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-1923\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-chevron-down\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-chevron-up\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Antibacterial Activity<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1923\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-1923\"><p><em>Gram-positive facultative bacteria<\/em><\/p>\n<p><strong>Fosfomicina LUAR<\/strong> is very active on methicillin-resistant S.aureus, whether community (CAMRSA) or hospital (HAMRSA). The MIC50 ranges from 1 to 2 mg\/L and the MIC90 ranges from 16 to 32 mg\/L. Coagulase-negative <strong>staphylococci<\/strong> such as S. epidermidis, whether or not they are resistant to methicillin, are sensitive, as are S. haemolyticus and S. hominis, although the latter have somewhat higher MICs. However, S.cohnii, S. warneri, S. capitis and notably S.saprophyticus have elevated MICs, frequently greater than 128 mg\/L. The differences in activity of <strong>Fosfomycin <\/strong>on different species of coagulase-negative <strong>staphylococci<\/strong> are attributed to different permeation capacity.<\/p>\n<p>MICs for <strong>pneumococci<\/strong>, viridans group <strong>streptococci<\/strong> and S.agalactiae are variable but in the range of sensitivity. The sensitivity of <strong>enterococci<\/strong> to <strong>Fosfomycin <\/strong>is unpredictable. MICs vary between 2 and &gt;128 mg\/L but more than 50% are sensitive.<\/p>\n<p>The activity of <strong>Fosfomicina LUAR<\/strong> against Listeria spp and most Corynebacterium spp (except C.striatum) is good. MIC in the sensitivity range has been verified in strains of C.urealyticum, the agent of fouling cystitis in humans, canines, and felines. Nocardia spp isolates are consistently resistant.<\/p>\n<p><em>Aerobic and facultative Gram-negative bacilli<\/em><\/p>\n<p>Enterobacteriaceae are sensitive to <strong>Fosfomicina LUAR<\/strong> with MIC between 0.25 and 16 mg\/L. It is important to highlight the activity on <strong>E.coli<\/strong>, K.pneumoniae, Salmonella spp, Shigella spp. K.oxytoca, Enterobacter spp, Providencia spp, Morganella morganii and Serratia spp, whose MICs range from 16 to 64 mg\/L, are less sensitive.<\/p>\n<p><strong>Gram-negative bacteria<\/strong> such as Campylobacter jejunii, Yersinia spp and Vibrio spp, are sensitive to <strong>Fosfomycin<\/strong>. Activity on Legionella, Pasteurella and Bartonella is effective although moderate. With respect to non-fermenting <strong>Gram-negative bacilli<\/strong>, more than 50-60% of P. aeruginosa isolates are sensitive.<\/p>\n<p><em>Anaerobes<\/em><\/p>\n<p><strong>Fosfomicina LUAR<\/strong> acts on Veillonella spp and Fusobacterium spp, with variable MIC values (0.12 to 32 mg\/L), has moderate activity (MIC 16-64 mg\/L) on Peptococous spp, Clostridium spp and Prevotella spp.<\/p>\n<p><em><br \/>Activity on multiresistant bacteria in Argentina<\/em><\/p>\n<p>Two research papers were recently presented by J M Casellas, the first at the Argentine Congress of Microbiology 2010 and the second at the Congress of the Pan American Association of Infectious Diseases in Punta del Este 2011, in which he showed the activity of <strong>Fosfomycin<\/strong> higher than 98% on isolates of <strong>E.coli<\/strong> and K.pneumoniae, producers of <strong>BLEE<\/strong> and carbapenemases, recovered from different sources in Argentina. It was also observed that more than 50% of multiresistant isolates of P.aeruginosa were sensitive to <strong>Fosfomycin<\/strong>, as well as all the strains of MRSA and S.epidermidis tested.<\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1924\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-1924\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-chevron-down\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-chevron-up\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Downloads<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1924\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-1924\"><p><a href=\"https:\/\/laboratoriosluar.com\/wp-content\/uploads\/2024\/07\/prospecto.webp\">Prospectus<\/a><\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<script type=\"application\/ld+json\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Presentation\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p><strong>Fosfomicina LUAR Intravenous Injectable 1 g<\\\/strong> is presented in boxes containing 10 and 100 vials.<\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Efficiency\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>In cases <strong>of severe hospital infections<\\\/strong>, the use of <strong>Fosfomycin<\\\/strong> in association with other antibiotics is essential to avoid the selection of resistant mutants (chromosomal acquired resistance) as much as possible. Associations with <strong>penicillins<\\\/strong>, <strong>cephalosporins<\\\/strong>, <strong>aminoglycosides<\\\/strong>, <strong>colistin<\\\/strong>, <strong>vancomycin<\\\/strong>, are always synergistic and never antagonistic.<\\\/p>\\n<p><strong>Fosfomycin sodium<\\\/strong> is used in <strong>complicated or severe infections<\\\/strong> caused by germs sensitive to the drug (Enterococcus faecalis, Streptococcus pneumoniae, methicillin-resistant Staphylococcus, Citrobacter spp , Escherichia coli, Haemophilus influenzae, Klebsiella spp, Neisseria meningitidis, Pasteurella spp, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Pseudomonas spp).<\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Antibacterial Activity\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p><em>Gram-positive facultative bacteria<\\\/em><\\\/p>\\n<p><strong>Fosfomicina LUAR<\\\/strong> is very active on methicillin-resistant S.aureus, whether community (CAMRSA) or hospital (HAMRSA). The MIC50 ranges from 1 to 2 mg\\\/L and the MIC90 ranges from 16 to 32 mg\\\/L. Coagulase-negative <strong>staphylococci<\\\/strong> such as S. epidermidis, whether or not they are resistant to methicillin, are sensitive, as are S. haemolyticus and S. hominis, although the latter have somewhat higher MICs. However, S.cohnii, S. warneri, S. capitis and notably S.saprophyticus have elevated MICs, frequently greater than 128 mg\\\/L. The differences in activity of <strong>Fosfomycin <\\\/strong>on different species of coagulase-negative <strong>staphylococci<\\\/strong> are attributed to different permeation capacity.<\\\/p>\\n<p>MICs for <strong>pneumococci<\\\/strong>, viridans group <strong>streptococci<\\\/strong> and S.agalactiae are variable but in the range of sensitivity. The sensitivity of <strong>enterococci<\\\/strong> to <strong>Fosfomycin <\\\/strong>is unpredictable. MICs vary between 2 and &gt;128 mg\\\/L but more than 50% are sensitive.<\\\/p>\\n<p>The activity of <strong>Fosfomicina LUAR<\\\/strong> against Listeria spp and most Corynebacterium spp (except C.striatum) is good. MIC in the sensitivity range has been verified in strains of C.urealyticum, the agent of fouling cystitis in humans, canines, and felines. Nocardia spp isolates are consistently resistant.<\\\/p>\\n<p><em>Aerobic and facultative Gram-negative bacilli<\\\/em><\\\/p>\\n<p>Enterobacteriaceae are sensitive to <strong>Fosfomicina LUAR<\\\/strong> with MIC between 0.25 and 16 mg\\\/L. It is important to highlight the activity on <strong>E.coli<\\\/strong>, K.pneumoniae, Salmonella spp, Shigella spp. K.oxytoca, Enterobacter spp, Providencia spp, Morganella morganii and Serratia spp, whose MICs range from 16 to 64 mg\\\/L, are less sensitive.<\\\/p>\\n<p><strong>Gram-negative bacteria<\\\/strong> such as Campylobacter jejunii, Yersinia spp and Vibrio spp, are sensitive to <strong>Fosfomycin<\\\/strong>. Activity on Legionella, Pasteurella and Bartonella is effective although moderate. With respect to non-fermenting <strong>Gram-negative bacilli<\\\/strong>, more than 50-60% of P. aeruginosa isolates are sensitive.<\\\/p>\\n<p><em>Anaerobes<\\\/em><\\\/p>\\n<p><strong>Fosfomicina LUAR<\\\/strong> acts on Veillonella spp and Fusobacterium spp, with variable MIC values (0.12 to 32 mg\\\/L), has moderate activity (MIC 16-64 mg\\\/L) on Peptococous spp, Clostridium spp and Prevotella spp.<\\\/p>\\n<p><em><br \\\/>Activity on multiresistant bacteria in Argentina<\\\/em><\\\/p>\\n<p>Two research papers were recently presented by J M Casellas, the first at the Argentine Congress of Microbiology 2010 and the second at the Congress of the Pan American Association of Infectious Diseases in Punta del Este 2011, in which he showed the activity of <strong>Fosfomycin<\\\/strong> higher than 98% on isolates of <strong>E.coli<\\\/strong> and K.pneumoniae, producers of <strong>BLEE<\\\/strong> and carbapenemases, recovered from different sources in Argentina. It was also observed that more than 50% of multiresistant isolates of P.aeruginosa were sensitive to <strong>Fosfomycin<\\\/strong>, as well as all the strains of MRSA and S.epidermidis tested.<\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Downloads\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p><a href=\\\"https:\\\/\\\/laboratoriosluar.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/prospecto.webp\\\">Prospectus<\\\/a><\\\/p>\\n\"}}]}<\/script>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5399476 e-flex e-con-boxed e-con e-parent\" data-id=\"5399476\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0e6ac1b e-con-full e-flex e-con e-child\" data-id=\"0e6ac1b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-60eacc7 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"60eacc7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Contact information<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-889ed3c elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"889ed3c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>You can make your inquiries through our different channels:<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-46d5575 elementor-widget elementor-widget-button\" data-id=\"46d5575\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/laboratoriosluar.com\/en\/contact\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contact<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Infectology Fosfomicina LUAR 1g injection Fosfomicina LUAR is active on methicillin-resistant staphylococci, BLEE- or carbapenemase-producing enterobacteria (such as KPC) and 50% of pseudomonas aeruginosa. Learn more About Fosfomicina LUAR It contains Fosfomycin sodium as active ingredient, and due to the appearance of strains resistant to conventional antibiotic therapies, it is used in association with other&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1284,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"class_list":["post-1327","page","type-page","status-publish","hentry"],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"mrmkt","author_link":"https:\/\/laboratoriosluar.com\/en\/author\/mrmkt\/"},"rttpg_comment":0,"rttpg_category":" <a href=\"https:\/\/laboratoriosluar.com\/en\/?taxonomy=translation_priority&#038;term=opcional-en\" rel=\"tag\">Opcional<\/a>","rttpg_excerpt":"Infectology Fosfomicina LUAR 1g injection Fosfomicina LUAR is active on methicillin-resistant staphylococci, BLEE- or carbapenemase-producing enterobacteria (such as KPC) and 50% of pseudomonas aeruginosa. Learn more About Fosfomicina LUAR It contains Fosfomycin sodium as active ingredient, and due to the appearance of strains resistant to conventional antibiotic therapies, it is used in association with other...","_links":{"self":[{"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/pages\/1327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/comments?post=1327"}],"version-history":[{"count":3,"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/pages\/1327\/revisions"}],"predecessor-version":[{"id":1441,"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/pages\/1327\/revisions\/1441"}],"up":[{"embeddable":true,"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/pages\/1284"}],"wp:attachment":[{"href":"https:\/\/laboratoriosluar.com\/en\/wp-json\/wp\/v2\/media?parent=1327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}